GLYPRESSIN FERRING PDF

The white, freeze-dried powder contains terlipressin acetate. Glypressin Injection is used in the treatment of bleeding oesophageal varices. Bleeding oesophageal varices are enlarged blood vessels that form in the stomach or oesophagus as a complication of liver disease. They may burst and bleed and this is a serious and life-threatening condition. When injected into the bloodstream, the active ingredient, terlipressin acetate is broken down to release a substance called lysine vasopressin.

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To view the changes to a medicine you must sign up and log in. Name of the medicinal product 2. Hyponatraemia if fluid not monitored. Gastroenterology — Ferring Corporate Pregnancy, puerperium and perinatal conditions. Topical PENTASA formulations enemas and suppositories enable active mesalazine to remain in contact with the inflamed mucosa for several hours. These effects are due to reflexogenic inhibition of cardiac activity via the vagus nerve due to the elevated blood pressure.

Reporting suspected adverse reactions after authorisation of the medicinal product is important. Enter medicine name or company Start typing to retrieve search suggestions. It is not known whether terlipressin is excreted in human breast milk. Respiratory ferring Respiratory failure. There are no pre-clinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.

By continuing to browse the site you are agreeing to our policy on the use of cookies. For the full list of excipients, see section 6. Any unused product or waste material should be disposed of in accordance with local requirements. This global corporate website provides general information about the global Ferring Group.

Intestinal ischaemia Peripheral cyanosis Hot flushes. Gastroenterology Not all products or indications are licensed in every country and may be subject to further local variations. The hypotensive effect of non-selective beta-blockers on the portal vein is increased with terlipressin.

For advice on medical issues please consult your local medical practitioner. Concomitant treatment with medicinal products with a known bradycardic effect e. Marketing authorisation holder 8. Find out more here. Unused drug and waste should be destroyed in accordance with local requirements. In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.

Last updated on eMC: Lysine vasopressin reaches maximum plasma levels about 1 — 2 hours following intravenous administration and has a duration of activity of 4 — 6 hours. Caution should be exercised in treating patients with hypertension or recognised heart disease.

Particular caution should be exercised in the treatment of children and elderly patients, as experience is limited in these groups. Marketing authorisation number s 9. To bookmark a medicine you must sign up and log in.

Glypressin is indicated in the treatment of bleeding oesophageal varices. Healthcare professionals are asked to ferringg any suspected adverse reactions via the Yellow Card Scheme, website: Glypressin has been shown to cause uterine contractions and increased intrauterine pressure in early pregnancy and may decrease uterine blood flow.

Show table of contents Hide table of contents 1. There is no data available regarding dosage recommendation in these special patient categories. Atrial fibrillation Ventrical extrasystoles Tachycardia Chest pain Myocardial infarction Fluid overload with pulmonary oedema Torsade fetring pointes Cardiac failure. Areas of interest Ways to collaborate How?

No studies on the effects on the ability to drive and use machines have been performed. Blood pressure, heart rate and fluid balance should be monitored during treatment. The treatment should be maintained until bleeding has been controlled for 24 hours, but up to a maximum of 48 hours. Sodium chloride Acetic acid Sodium acetate Water for injections. To email a medicine you must sign up and log in. Posology In acute variceal bleeding: For specific product information please consult the summary of product characteristics SPC.

Sign Up Log In Cancel. Ferring Corporate Country-Territory websites. After the initial dose, the dose can be adjusted to 1 mg i. It shows a biphasic plasma level curve which indicates that a two compartment model can be applied.

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To view the changes to a medicine you must sign up and log in. Name of the medicinal product 2. Hyponatraemia if fluid not monitored. Gastroenterology — Ferring Corporate Pregnancy, puerperium and perinatal conditions. Topical PENTASA formulations enemas and suppositories enable active mesalazine to remain in contact with the inflamed mucosa for several hours.

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As the situation regarding COVID novel coronavirus disease is evolving rapidly, Ferring is committed to following appropriate global, regional and local medical authority guidance to prevent infection spread and to keep patients, our employees and their families safe. In line with the current positions from scientific societies on patients seeking or undergoing fertility treatment, including from the European Society of Human Reproduction and Embryology ESHRE and the American Society of Reproductive Medicine ASRM , Ferring is now working to temporarily halt recruitment or postpone our clinical trials in fertility as necessary in impacted countries. In addition to policies to protect our employees and prevent infection spread, we have also put in place plans to avoid disruption in manufacturing and ensure continuity of supply of our treatments to doctors and patients around the world. However, we unfortunately cannot rule out a future impact on our business as the situation is rapidly evolving. Our thoughts are with the people and families affected by COVID around the world, including our patients and those working tirelessly to address the pandemic. We remain committed to building families worldwide and look forward to continuing our research in the area of reproductive medicine and maternal health when the current situation improves.

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